Journal of Tissue Engineering and Reconstructive Surgery››2024,Vol. 20››Issue (2): 254-.

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The pathogenesis and therapeutic strategies for congenital melanocytic nevi

    • Online:2024-04-30Published:2024-05-16

    Abstract:

    Congenital melanocytic nevus is a common skin developmental abnormality that can occur in any part of the
    body where melanocytes are present. Its occurrence is closely related to somatic cell mutations, regulated by multiple
    signaling pathways, and has diverse clinical manifestations. Surgical excision and dilator are still the main treatments for
    CMN, and laser therapy is a powerful mean to eliminate pigmentation and remove satellite lesions. Targeted therapy and
    immunotherapy are becoming a new direction for the treatment of congenital melanin giant nevi.

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