Abstract:ObjectiveTo explore intraoperative bleeding of patients with early stage hepatocellular carcinoma which may relate to perioperative events and the prognosis.MethodsA retrospective analysis was performed on 222 patients with early stage hepatocellular carcinoma who underwent surgical resection in Tianjin Medical University Cancer Hospital from January 2008 to December 2013. According to the receiver operating characteristic curve analysis of the volume of intraoperative blood loss, 185 cases with blood loss 200 mL or less were assigned into group A and 37 cases with blood loss more than 200 mL into group B. Hospital stay, complication and overall survival were compared between two groups.ResultsThere were no significant difference in gender, age, preoperative platelet counting, prothrombin time and total serum bilirubin and diameter and number of tumor between two groups statistically (P>0.05). Longer median survival time of the patients, shorter hospital stay, less cases with ascites and infection were found in group A when compared those in group B (P<0.05).ConclusionsFor patients with early stage hepatocellular carcinoma, intraoperative bleeding may be a negative factor for the perioperative complications and long term survival. It is necessary to reduce the bleeding during hepatectomy.

Key words:Hepatocellular carcinoma,Hepatectomy,Intraoperative hemorrhage,Complications,Prognosis