胆囊腺肌症的发病机制及诊治研究进展

摘要/Abstract

摘要：

胆囊腺肌症（gallbladder adenomyomatosis,GA）是一种临床上较少见、病因及发病机制不明的良性疾病。随着影像检测技术的发展,其诊断有进一步提高。部分学者认为GA与胆囊癌的形成有关,但尚存争议。GA的治疗,有主张胆囊切除,以预防其恶变,也有学者认为部分GA可行随访。目前尚无共识。本文对GA的病因、发病机制和诊治进展进行综述。

中图分类号:

R735.8

陈炫武, 杨传玉, 蒋敏杰 , 杜卫东. 胆囊腺肌症的发病机制及诊治研究进展[J]. 外科理论与实践, 2022, 27(01): 87-90.

CHEN Xuanwu, YANG Chuanyu, JIANG Minjie, DU Weidong. Progress of study on gallbladder adenomyomatosis: pathogenesis, diagnosis and treatment[J]. Journal of Surgery Concepts & Practice, 2022, 27(01): 87-90.

参考文献37

[1]	Jutras JA. Hyperplastic cholecystoses;Hickey lecture,1960[J]. Am J Roentgenol Radium Ther Nucl Med, 1960, 83:795-827.
[2]	Mahajan A, Sripathi S. Gallbladder adenomyomatosis mimicking carcinoma: a diagnostic dilemma[J]. J Glob Oncol, 2016, 2(5):341-345.
[3]	Keisuke E, Tatsuki M, Yugo T, et al. Adenomyomatosis of the gallbladder with pancreaticobiliary maljunction in a child[J]. J Pediatr Gastroentrol Nutr, 2018, 67(4):e82.
[4]	Parolini F, Indolfi G, Magne MG, et al. Adenomyomatosis of the gallbladder in childhood: a systematic review of the literature and an additional case report[J]. World J Clin Pediatr, 2016, 5(2):223-227. doi:10.5409/wjcp.v5.i2.223pmid:27170933
[5]	Chen CB, Nasser KM. Gallbladder Adenomyomatosis in an Infant[J]. ACG Case Rep J, 2020, 7(7):e00433. doi:10.14309/crj.0000000000000433 URL
[6]	Eroğlu N, Erduran E, Imamoğlu M, et al. Diffuse adenomyomatosis of the gallbladder in a child[J]. J Pediatr Hematol Oncol, 2016, 38(8):307-309.
[7]	殷雷, 邱法波, 吴昌亮, 等. 中国近30年胆囊腺肌增生症流行病学特征及诊治经验[J]. 中国现代医学杂志, 2012, 22(18):66-70.
[8]	Kim JH, Jeong IH, Han JH, et al. Clinical/pathological analysis of gallbladder adenomyomatosis; type and pathogenesis[J]. Hepatogastroenterology, 2010, 57(99-100):420-425.
[9]	Charles H, Pilgrim C, Groeschl RT, et al. Modern perspective on factors predisposing to the development of gallbladder cancer[J]. HPB, 2013, 15(11):839-844. doi:10.1111/hpb.12046pmid:23458506
[10]	Pang L, Zhang Y, Wang Y, et al. Pathogenesis of gallbladder adenomyomatosis and its relationship with early-stage gallbladder carcinoma: an overview[J]. Braz J Med Biol Res, 2018, 51(6):7411.
[11]	Jacobs E, Ardichvili D, D′Avanzo E, et al. Cyst of the gallbladder[J]. Dig Dis Sci, 1991, 36(12):1976-1802.
[12]	王晓瑾, 龚彪, 别里克·扣肯, 等. 内镜下胰胆管造影术对胆胰管汇合异常的诊断及治疗价值[J]. 内科理论与实践, 2016, 11(1):38-41.
[13]	Lee SW, Yun SP, Seo HI. Heterotopic pancreas of the gallbladder associated with segmental adenomyomatosis of the gallbladder[J]. J Korean Surg Soc, 2013, 84(5):309-311. doi:10.4174/jkss.2013.84.5.309 URL
[14]	Suzuki K, Abe K, Ohbu M. A Resected gallbladder carcinoma coexisting with adenomyomatosis involving varied degrees of intraepithelial dysplasia:a case report and li-terature review[J]. Surg Laparosc Endosc Percutan Tech, 2019, 29(4):290-296.
[15]	Ootani T, Shirai Y, Tsukada K, et al. Relationship between gallbladder carcinoma and the segmental type of adenomyomatosis of the gallbladder[J]. Cancer, 1992, 69(11):2647-2652. pmid:1571894
[16]	Nabatame N, Shirai Y, Nishimura A, et al. High risk of gallbladder carcinoma in elderly patients with segmental adenomyomatosis of the gallbladder[J]. J Exp Clin Cancer Res, 2004, 23(4):593-598.
[17]	Valle JW. BINGO: targeted therapy for advanced biliary-tract cancer[J]. Lancet Oncol, 2014, 15(8):778-780. doi:10.1016/S1470-2045(14)70238-4pmid:24852117
[18]	Müller BG, de Aretxabala X, González Domingo M. A review of recent data in the treatment of gallbladder cancer: what we know,what we do,and what should be done[J]. Am Soc Clin Oncol Educ Book, 2014:e165-170.
[19]	Ebata T, Ercolani G, Alvaro D, et al. Current status on cholangiocarcinoma and gallbladder cancer[J]. Liver Cancer, 2016, 6(1):59-65. doi:10.1159/000449493 URL
[20]	Lee HJ, Chung WS, Kim JY, et al. Chronic inflammation-related radiological findings of gallbladder adenomyomatosis[J]. Jpn J Radiol, 2020, 38(5):463-471. doi:10.1007/s11604-020-00931-7 URL
[21]	Hammad AY, Miura JT, Turaga KK, et al. A literature review of radiological findings to guide the diagnosis of gallbladder adenomyomatosis[J]. HPB (Oxford), 2016, 18(2):129-135. doi:10.1016/j.hpb.2015.09.006 URL
[22]	Miyoshi H, Inui K, Katano Y, et al. B-mode ultrasonographic diagnosis in gallbladder wall thickening[J]. J Med Ultrason (2001), 2021, 48(2):175-186.
[23]	Bang SH, Lee JY, Woo H, et al. Differentiating between adenomyomatosis and gallbladder cancer: revisiting a comparative study of high-resolution ultrasound,multidetector CT, and MR imaging[J]. Korean J Radiol, 2014, 15(2):226-234. doi:10.3348/kjr.2014.15.2.226 URL
[24]	Kim HJ, Park JH, Park DI, et al. Clinical usefulness of endoscopic ultrasonography in the differential diagnosis of gallbladder wall thickening[J]. Dig Dis Sci, 2012, 57(2):508-515. doi:10.1007/s10620-011-1870-0 URL
[25]	Miwa H, Numata K, Sugimori K, et al. Differential diagnosis of gallbladder polypoid lesions using contrast-enhanced ultrasound[J]. Abdom Radiol(NY), 2019, 44(4):1367-1378.
[26]	Negrao de Figueiredo G, Mueller-Peltzer K, Zengel P, et al. Diagnostic perfor-mance of contrast-enhanced ultrasound (CEUS) for the evaluation of gallbladder diseases1[J]. Clin Hemorheol Microcirc, 2018, 69(1-2):83-91. doi:10.3233/CH-189116 URL
[27]	Chen LD, Huang Y, Xie XH, et al. Diagnostic nomogram for gallbladder wall thickening mimicking malignancy: Using contrast-enhanced ultrasonography or multi-detector computed tomography?[J]. Abdom Radiol(NY), 2017, 42(10):2436-2446.
[28]	Gerstenmaier JF, Hoang KN, Gibson RN. Contrast-enhanced ultrasound in gallbladder disease: A pictorial review[J]. Abdom Radiol(NY), 2016, 41(8):1640-1652.
[29]	Wang W, Fei Y, Wang F. Meta-analysis of contrast-enhanced ultrasonography for the detection of gallbladder carcinoma[J]. Med Ultrason, 2016, 18(3):281-328. doi:10.11152/mu.2013.2066.183.weipmid:27622402
[30]	Tang SS, Huang L, Wang Y, et al. Contrast-enhanced ultrasonography diagnosis of fundal localized type of gallbladder adenomyomatosis[J]. BMC Gastroenterol, 2015, 15:99. doi:10.1186/s12876-015-0326-y URL
[31]	Turkvatan A, Turkoglu MA, Ozogul Y, et al. Multidetector computed tomography diagnosis of adenomyomatosis of the gallbladder[J]. Turk J Gastroenterol, 2013, 24(3):286-289. doi:10.4318/tjg.2013.0534 URL
[32]	Kim BS, Oh JY, Nam KJ, et al. Focal thickening at the fundus of the gallbladder: computed tomography differentiation of fundal type adenomyomatosis and localized chronic cholecystitis[J]. Gut Liver, 2014, 8(2):219-223. doi:10.5009/gnl.2014.8.2.219 URL
[33]	Yang HK, Lee JM, Yu MH, et al. CT diagnosis of gallbladder adenomyomatosis: importance of enhancing mucosal epithelium, the “cotton ball sign”[J]. Eur Radiol, 2018, 28(9):3573-3582. doi:10.1007/s00330-018-5412-4 URL
[34]	Bonatti M, Vezzali N, Lombardo F, et al. Gallbladder adenomyomatosis:imaging findings, tricks and pitfalls[J]. Insights Imaging, 2017, 8(2):243-253. doi:10.1007/s13244-017-0544-7 URL
[35]	Tomizawa M, Shinozaki F, Fugo K, et al. Negative signals for adenomyomatosis of the gallbladder upon diffusion-weighted whole body imaging with background body signal suppression/T2-weighted image fusion analysis[J]. Exp Ther Med, 2016, 11(5):1777-1780. pmid:27168802
[36]	Pellino G, Sciaudone G, Candilio G, et al. Stepwise approach and surgery for gallbladder adenomyomatosis: a mini-review[J]. Hepatobiliary Pancreat Dis Int, 2013, 12(2):136-142. doi:10.1016/S1499-3872(13)60022-3 URL
[37]	Golse N, Lewin M, Rode A, et al. Gallbladder adenomyomatosis: diagnosis and management[J]. J Visc Surg, 2017, 154(5):345-353. doi:S1878-7886(17)30060-7pmid:28844704

胆囊腺肌症的发病机制及诊治研究进展

Progress of study on gallbladder adenomyomatosis: pathogenesis, diagnosis and treatment

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