Cost of hospitalization of patients with hepatolenticular degeneration in southwest of China: data analysis during 2005-2020

Abstract

Abstract:

ObjectiveTo analyze the hospitalization cost of the patients with hepatolenticular degeneration in southwest of China.MethodsThe data of hospitalization cost of the patients with hepatolenticular degeneration were acquired from electronic medical record system in West China Fourth Hospital from 2005 to 2020. Multiple linear regression analysis was utilized for analyzing the factors of hospitalization cost retrospectively, and covariance analysis was used for controlling the confounding factors. SPSS 20.0 (IBM) was applied for data analysis.ResultsA total of 346 patients with hepatolenticular degeneration were enrolled in our analysis. The year of admission, age, number of comorbidities, days of hospitalization, and complication of decompensated liver cirrhosis were the factors to influence the cost of hospitalization. After the confounding factors were adjusted, the hospitalization cost grew following the increase of comorbidity number, and complication of decompensated liver cirrhosis also led to the increase of hospitalization cost. The hospitalization cost of 2005-2006 and 2007-2008 were lower than those in the rest of years.ConclusionsHospitalization cost of the patients with hepatolenticular degeneration in southwest of China were influenced by number of comorbidities, complication of decompensated liver cirrhosis, and year to admit. It was important to reduce the occurrence of complication and decompensated liver cirrhosis, as to reduce the cost of hospitalization.

Key words:Hepatolenticular degeneration,Wilson disease,Cost,Disease burden,Comorbidity

CLC Number:

R742.4

HONG Peiwei, CONG Xue, XU Yanming. Cost of hospitalization of patients with hepatolenticular degeneration in southwest of China: data analysis during 2005-2020[J]. Journal of Internal Medicine Concepts & Practice, 2021, 16(05): 315-318.

Figures/Tables4

变量	β	下限	上限	P
就诊年份	0.16	260.32	590.02	<0.001
年龄	0.09	16.54	78.92	0.003
性别	-0.01	-707.42	527.52	0.775
住院前使用驱铜药物	0.00	-616.44	704.99	0.895
首发症状部位	-0.01	-173.48	127.84	0.766
合并症数量	0.13	464.09	1 258.72	<0.001
住院天数	0.82	310.01	359.95	<0.001
肝硬化失代偿	0.09	491.64	2 150.05	0.002

合并症数量	n	均数	标准误	P （vs.0)	P （vs.1)	P （vs.2)	P（vs. ≥3)
0	191	8 313.22	207.72		0.222	0.048	<0.001
1	104	8 741.79	276.12	0.222		0.259	<0.001
2	39	9 345.03	464.73	0.048	0.259		<0.001
≥3	12	12 718.24	811.39	<0.001	<0.001	<0.001
F	7.319
P	<0.001

项目	2005—2006	2007—2008	2009—2010	2011—2012	2013—2014	2015—2016	2017—2018	2019—2020
n	12	29	37	44	54	49	68	53
均数	5 445.51	6 489.49	8 650.85	8 402.34	9 275.34	8 767.06	9631.49	9 157.05
标准误	805.59	531.25	475.84	422.46	379.96	402.02	342.68	399.62
F	6.26
P	<0.001
P(vs.2005—2006)	-	0.28	0.00	0.00	0.00	0.00	0.00	0.00
P(vs.2007—2008)	0.28	-	0.00	0.00	0.00	0.00	0.00	0.00
P(vs.2009—2010)	0.00	0.00	-	0.69	0.30	0.85	0.10	0.43
P(vs.2011—2012)	0.00	0.00	0.69	-	0.12	0.53	0.03	0.20
P(vs.2013—2014)	0.00	0.00	0.30	0.12	-	0.36	0.49	0.83
P(vs.2015—2016)	0.00	0.00	0.85	0.53	0.36	-	0.10	0.49
P(vs.2017—2018)	0.00	0.00	0.10	0.03	0.49	0.10	-	0.36
P(vs.2019—2020)	0.00	0.00	0.43	0.20	0.83	0.49	0.36	-

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