非胰岛细胞肿瘤所致的低血糖临床诊治进展

摘要/Abstract

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R736

张婕, 陆洁莉. 非胰岛细胞肿瘤所致的低血糖临床诊治进展[J]. 内科理论与实践, 2023, 18(04): 256-260.

ZHANG Jie, LU Jieli. Clinical diagnosis and treatment progress of hypoglycemia caused by non-islet cell tumors[J]. Journal of Internal Medicine Concepts & Practice, 2023, 18(04): 256-260.

参考文献50

[1]	de Groot JW, Rikhof B, van Doorn J, et al. Non-islet cell tumour-induced hypoglycaemia: a review of the literature including two new cases[J]. Endocr Relat Cancer, 2007, 14(4): 979-993. doi:10.1677/ERC-07-0161 URL
[2]	Baldwin RS. Hypoglycemia with neoplasia (doege-potter syndrome)[J]. Wis Med J, Wis Med J, 1965, 64: 185-189.
[3]	Bodnar TW, Acevedo MJ, Pietropaolo M. Management of non-islet-cell tumor hypoglycemia: a clinical review[J]. J Clin Endocrinol Metab, 2014, 99(3): 713-722. doi:10.1210/jc.2013-3382pmid:24423303
[4]	Fukuda I, Hizuka N, Ishikawa Y, et al. Clinical features of insulin-like growth factor-Ⅱ producing non-islet-cell tumor hypoglycemia[J]. Growth Horm IGF Res, 2006, 16(4): 211-216. doi:10.1016/j.ghir.2006.05.003pmid:16860583
[5]	Rastogi MV, Desai N, Quintos JB. Non-islet-cell tumor hypoglycemia and lactic acidosis in a child with congenital HIV and Burkitt’s lymphoma[J]. J Pediatr Endocrinol Metab, 2008, 21(8): 805-810.
[6]	Agus MS, Katz LE, Satin-Smith M, et al. Non-islet-cell tumor associated with hypoglycemia in a child: successful long-term therapy with growth hormone[J]. J Pediatr, 1995, 127(3): 403-407. doi:10.1016/S0022-3476(95)70071-4 URL
[7]	Korn E, Van Hoff J, Buckley P, et al. Secretion of a large molecular-weight form of insulin-like growth factor by a primary renal tumor[J]. Med Pediatr Oncol, 1995, 24(6): 392-396. pmid:7715546
[8]	Teale JD, Marks V. Glucocorticoid therapy suppresses abnormal secretion of big IGF-Ⅱ by non-islet cell tumours inducing hypoglycaemia(NICTH)[J]. Clin Endocrinol (Oxf), 1998, 49(4): 491-498. doi:10.1046/j.1365-2265.1998.00564.x URL
[9]	Phillips LS, Robertson DG. Insulin-like growth factors and non-islet cell tumor hypoglycemia[J]. Metabolism, 1993, 42(9): 1093-1101. doi:10.1016/0026-0495(93)90265-P URL
[10]	陆洁莉, 赵咏桔, 唐金凤, 等. 胰岛素样生长因子Ⅱ过度分泌引起的非胰岛细胞肿瘤性低血糖——2例报告与文献复习[J]. 中华内分泌代谢杂志, 2004, 20(3): 234-235.
[11]	陆洁莉, 刘建民, 方文强, 等. 非胰岛细胞肿瘤所致低血糖一例及文献复习[J]. 中华内分泌代谢杂志, 2016, 32(4): 330-334.
[12]	Shapiro ET, Bell GI, Polonsky KS, et al. Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-Ⅱ[J]. J Clin Invest, 1990, 85(5): 1672-1679. doi:10.1172/JCI114619pmid:2159026
[13]	Rosseel L, De Leu N, van Hecke W, et al. A rare case of hypoglycemia in a patient with elevated right hemidiaphragm[J]. BMJ Case Rep, 2012, 2012: bcr0320125972.
[14]	Zafar H, Takimoto CH, Weiss G. Doege-Potter syndrome: hypoglycemia associated with malignant solitary fibrous tumor[J]. Med Oncol, 2003, 20(4): 403-408. pmid:14716039
[15]	Dynkevich Y, Rother KI, Whitford I, et al. Tumors, IGF-2, and hypoglycemia: insights from the clinic, the laboratory, and the historical archive[J]. Endocr Rev, 2013, 34(6): 798-826. doi:10.1210/er.2012-1033pmid:23671155
[16]	Kalebi AY, Hale MJ, Wong ML, et al. Surgically cured hypoglycemia secondary to pleural solitary fibrous tumour: case report and update review on the Doege-Potter syndrome[J]. J Cardiothorac Surg, 2009, 4: 45. doi:10.1186/1749-8090-4-45pmid:19689813
[17]	Daughaday WH, Emanuele MA, Brooks MH, et al. Synthesis and secretion of insulin-like growth factor Ⅱ by a leiomyosarcoma with associated hypoglycemia[J]. N Engl J Med, 1988, 319(22): 1434-1440. doi:10.1056/NEJM198812013192202 URL
[18]	Baxter RC. The role of insulin-like growth factors and their binding proteins in tumor hypoglycemia[J]. Horm Res, 1996, 46(4-5): 195-201. doi:10.1159/000185023pmid:8950621
[19]	Bertherat J, Logié A, Gicquel C, et al. Alterations of the 11p15 imprinted region and the IGFs system in a case of recurrent non-islet-cell tumour hypoglycaemia (NICTH)[J]. Clin Endocrinol (Oxf), 2000, 53(2): 213-220. doi:10.1046/j.1365-2265.2000.01064.x URL
[20]	Tani Y, Tateno T, Izumiyama H, et al. Defective expression of prohormone convertase 4 and enhanced expression of insulin-like growth factor Ⅱ by pleural solitary fibrous tumor causing hypoglycemia[J]. Endocr J, 2008, 55(5): 905-911. doi:10.1507/endocrj.K08E-062 URL
[21]	Hoekman K, van Doorn J, Gloudemans T, et al. Hypoglycaemia associated with the production of insulin-like growth factor Ⅱ and insulin-like growth factor binding protein 6 by a haemangiopericytoma[J]. Clin Endocrinol (Oxf), 1999, 51(2): 247-253. doi:10.1046/j.1365-2265.1999.00833.x URL
[22]	Zachariah S, Brackenridge A, Shojaee-Moradie F, et al. The mechanism of non-islet cell hypoglycaemia caused by tumour-produced IGF-Ⅱ[J]. Clin Endocrinol (Oxf), 2007, 67(4): 637-638. doi:10.1111/cen.2007.67.issue-4 URL
[23]	LeRoith D, Roberts CT Jr. The insulin-like growth factor system and cancer[J]. Cancer Lett, 2003, 195(2): 127-137. doi:10.1016/s0304-3835(03)00159-9pmid:12767520
[24]	Cryer PE, Axelrod L, Grossman AB, et al. Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline[J]. J Clin Endocrinol Metab, 2009, 94(3): 709-728. doi:10.1210/jc.2008-1410pmid:19088155
[25]	Kageyama K, Moriyama T, Hizuka N, et al. Hypoglycemia associated with big insulin-like growth factor Ⅱ produced during development of malignant fibrous histiocytoma[J]. Endocr J, 2003, 50(6): 753-758. doi:10.1507/endocrj.50.753 URL
[26]	Tsuro K, Kojima H, Okamoto S, et al. Glucocorticoid therapy ameliorated hypoglycemia in insulin-like growth factor-Ⅱ-producing solitary fibrous tumor[J]. Intern Med, 2006, 45(8): 525-529. doi:10.2169/internalmedicine.45.1611 URL
[27]	Bessell EM, Selby C, Ellis IO. Severe hypoglycaemia caused by raised insulin-like growth factor Ⅱ in disseminated breast cancer[J]. J Clin Pathol, 1999, 52(10): 780-781. doi:10.1136/jcp.52.10.780pmid:10674040
[28]	Escobar GA, Robinson WA, Nydam TL, et al. Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation[J]. BMC Cancer, 2007, 7: 13. doi:10.1186/1471-2407-7-13 URL
[29]	Barra WF, Castro G, Hoff AO, et al. Symptomatic hypoglycemia related to inappropriately high IGF-Ⅱ serum levels in a patient with desmoplastic small round cell tumor[J]. Case Rep Med, 2010, 2010: 684045.
[30]	Hunter SJ, Daughaday WH, Callender ME, et al. A case of hepatoma associated with hypoglycaemia and overproduction of IGF-Ⅱ(E-21): beneficial effects of treatment with growth hormone and intrahepatic adriamycin[J]. Clin Endocrinol (Oxf), 1994, 41(3): 397-401. doi:10.1111/cen.1994.41.issue-3 URL
[31]	Kishi K, Sonomura T, Sato M. Radiotherapy for hypoglycaemia associated with large leiomyosarcomas[J]. Br J Radiol, 1997, 70: 306-308. doi:10.1259/bjr.70.831.9166058 URL
[32]	Teale JD, Wark G. The effectiveness of different treatment options for non-islet cell tumour hypoglycaemia[J]. Clin Endocrinol (Oxf), 2004, 60(4): 457-460. doi:10.1111/cen.2004.60.issue-4 URL
[33]	Powter L, Phillips S, Husbands E. A case report of non-islet cell tumour hypoglycaemia associated with ovarian germ-cell tumour[J]. Palliat Med, 2013, 27(3): 281-283. doi:10.1177/0269216312462273pmid:23128903
[34]	Mukherjee S, Diver M, Weston PJ. Non islet cell tumor hypoglycaemia in a metastatic Leydig cell tumor[J]. Acta Oncol, 2005, 44(7): 761-763. pmid:16227169
[35]	Perros P, Simpson J, Innes JA, et al. Non-islet cell tumour-associated hypoglycaemia:¹¹¹In-octreotide imaging and efficacy of octreotide, growth hormone and glucocorticosteroids[J]. Clin Endocrinol (Oxf), 1996, 44(6): 727-731. doi:10.1046/j.1365-2265.1996.721542.x URL
[36]	Silveira LF, Bouloux PM, MacColl GS, et al. Growth hormone therapy for non-islet cell tumor hypoglycemia[J]. Am J Med, 2002, 113(3): 255-257. pmid:12208393
[37]	Teale JD, Blum WF, Marks V. Alleviation of non-islet cell tumour hypoglycaemia by growth hormone therapy is associated with changes in IGF binding protein-3[J]. Ann Clin Biochem, 1992, 29 Pt 3: 314-323.
[38]	Drake WM, Miraki F, Siddiqi A, et al. Dose-related effects of growth hormone on IGF-Ⅰ and IGF-binding protein-3 levels in non-islet cell tumour hypoglycaemia[J]. Eur J Endocrinol, 1998, 139(5): 532-536. pmid:9849819
[39]	Bourcigaux N, Arnault-Ouary G, Christol R, et al. Treatment of hypoglycemia using combined glucocorticoid and recombinant human growth hormone in a patient with a metastatic non-islet cell tumor hypoglycemia[J]. Clin Ther, 2005, 27(2): 246-251. doi:10.1016/j.clinthera.2005.02.004pmid:15811488
[40]	Baxter RC, Holman SR, Corbould A, et al. Regulation of the insulin-like growth factors and their binding proteins by glucocorticoid and growth hormone in nonislet cell tumor hypoglycemia[J]. J Clin Endocrinol Metab, 1995, 80(9): 2700-2708.
[41]	Sullivan DH, Carter WJ, Warr WR, et al. Side effects resulting from the use of growth hormone and insulin-like growth factor-Ⅰ as combined therapy to frail elderly patients[J]. J Gerontol A Biol Sci Med Sci, 1998, 53(3): M183-M187.
[42]	Scott K. Non-islet cell tumor hypoglycemia[J]. J Pain Symptom Manage, 2009, 37(4): e1-e3.
[43]	Föger B, Zapf J, Lechleitner M, et al. Prevention with glucocorticoids of extrapancreatic tumour-hypoglycaemia as a result of increased ‘big’ insulin-like growth factor Ⅱ[J]. J Intern Med, 1994, 236(6): 692-693. pmid:7989907
[44]	Goode PN, Farndon JR, Anderson J, et al. Diazoxide in the management of patients with insulinoma[J]. World J Surg, 1986, 10(4): 586-592. pmid:3019020
[45]	Davda R, Seddon BM. Mechanisms and management of non-islet cell tumour hypoglycaemia in gastrointestinal stromal tumour: case report and a review of published studies[J]. Clin Oncol (R Coll Radiol), 2007, 19(4): 265-268. doi:10.1016/j.clon.2006.12.008 URL
[46]	Davda R, Seddon BM. Mechanisms and management of non-islet cell tumour hypoglycaemia in gastrointestinal stromal tumour: case report and a review of published studies[J]. Clin Oncol (R Coll Radiol), 2007, 19(4): 265-268. doi:10.1016/j.clon.2006.12.008 URL
[47]	Sturrock ND, Selby C, Hosking DJ. Spontaneous hypoglycaemia in a noninsulin-dependent diabetes mellitus patient with disseminated pancreatic carcinoma[J]. Diabet Med, 1997, 14(4): 324-326. doi:10.1002/(ISSN)1096-9136 URL
[48]	Krishnan L, Clark J. Non-islet cell tumour hypoglycaemia[J]. BMJ Case Rep, 2011, 2011: bcr0220113914.
[49]	Ishikura K, Takamura T, Takeshita Y, et al. Cushing’s syndrome and big IGF-Ⅱ associated hypoglycaemia in a patient with adrenocortical carcinoma[J]. BMJ Case Rep, 2010, 2010: bcr07.
[50]	Morbois-Trabut L, Maillot F, De Widerspach-Thor A, et al. “Big IGF-Ⅱ”-induced hypoglycemia secondary to gastric adenocarcinoma[J]. Diabetes Metab, 2004, 30(3): 276-279. doi:10.1016/S1262-3636(07)70119-2pmid:15223980

非胰岛细胞肿瘤所致的低血糖临床诊治进展

Clinical diagnosis and treatment progress of hypoglycemia caused by non-islet cell tumors

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