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Erdem Goker

Memorial Sloan Kettering Cancer Center

20

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Phase II, randomized, double-blind placebo-controlled trial of nimotuzumab plus gemcitabine compared with gemcitabine alone in patients (pts) with advanced pancreatic cancer (PC).

2017 Journal of Clinical Oncology
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Traitement de patients diagnostiqués avec un adénocarcinome canalaire du pancréas au moyen de l'utilisation d'anticorps monoclonaux contre le récepteur de facteur de croissance épidermique (egfr)

2016
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methotrexate in patients with acute lymphocytic leukemia Defective transport as a mechanism of acquired resistance to

2011
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Drug Resistance In The Treatment of Cancer: Resistance mechanisms to antimetabolites

1998
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Capillary electrophoresis of methotrexate polyglutamates and its application in evaluation of γ-glutamyl hydrolase activity

1997 Journal of Chromatography B: Biomedical Sciences and Applications
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Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.

1997 Blood
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Resistance Mechanisms to Methotrexate in Tumors

1996 Stem Cells
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Intrinsic and Acquired Resistance to Methotrexate in Acute Leukemia

1996 The New England Journal of Medicine
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Amplification of the dihydrofolate reductase gene is a mechanism of acquired resistance to methotrexate in patients with acute lymphoblastic leukemia and is correlated with p53 gene mutations.

1995 Blood
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Acute monocytic leukemia: A myeloid leukemia subset that may be sensitive to methotrexate

1995 Leukemia
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