Clinical evaluation of the modified open wound sutureless labial gland biopsy technique for patient with Sjögren syndrome

Abstract

Abstract:

ObjectiveTo explore the clinical value of modified open-wound sutureless labial gland biopsy for patients with Sjögren syndrome.MethodsA total of 24 patients who underwent labial gland biopsy in our department from March 2023 to April 2025 were divided into the sutureless labial gland biopsy (SLSGB) group and the traditional labial salivary gland biopsy (TLSGB) group. The numerical rating scale (NRS) 0-10 was used to evaluate the postoperative recovery time and incision pain at 2 h, 1 d, and 7 d after surgery in both groups.ResultsThe postoperative recovery time score was (6.67±0.82) points in the TLSGB group and (2.00±0.00) points in the SLSGB group (P< 0.001). The NRS scores at 2 h, 1 d, and 7 d after surgery were (5.83±0.98), (2.67±0.52), and (2.00±0.63) points in the TLSGB group, and (1.72±0.46), 0, and 0 points in the SLSGB group, respectively. There were significant differences between the two groups at 2 h and 1 d after surgery (bothP<0.05), but there was no statistical difference at 7 d after surgery (P>0.05).ConclusionsOpen incision labial gland biopsy is less invasive, less prone to secondary injury, does not require suture removal, is easy to operate, and rarely causes complications. It can reduce significantly the economic and time costs and it’s more easily accepted by patients.

Key words:Sjögren syndrome,Sutureless labial gland biopsy,Postoperative recovery

CLC Number:

R593

CHEN Yabing, GAO Jie, XU Xia, ZHAO Dongbao. Clinical evaluation of the modified open wound sutureless labial gland biopsy technique for patient with Sjögren syndrome[J]. Journal of Internal Medicine Concepts & Practice, 2025, 20(04): 312-315.

Figures/Tables1

项目	TLSGB组(n=6)	SLSGB组(n=18)	P
术后恢复时间（d）	6.67±0.82	2.00±0.00	<0.001
NRS（分）
术后2 h	5.83±0.98	1.72±0.46	0.001
术后第1天	2.67±0.52	0.00±0.00	<0.010
术后第7天	2.00±0.63	0.00±0.00	0.090
红细胞沉降率(mm/h)	25.00±26.52	22.67±17.79	0.204
C反应蛋白(mg/L)	4.29±4.15	3.35±1.93	0.122
RF(U/mL)	32.25±39.79	29.79±46.19	0.938

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