学习经历
1986年，山东大学 微生物学专业 学士学位
1993年，日本 东京大学，微生物应用实验室， 生物化学与生物技术 硕士学位
1996年，日本 东京大学，微生物应用实验室， 生物化学与生物技术 博士学位

 

工作经历
2019年-至今，开云网页登录 ，长聘教授
2006年-至今，开云网页登录 系统生物医学研究院，研究员（博导）
2011年-至今， SCSB-AIST中日医学糖组学联合实验室，中方主任
2015年-2024年，开云网页登录 系统生物医学研究院，院工会主席
1996-2006年，日本产业技术综合研究所（AIST）及日本国立动物卫生研究所, 博士后/助理研究员
1986年-1989年，开云网页登录 生命科学与技术系，助教
在蛋白质糖基化修饰调控、糖基转移酶功能、疾病生物标志物发现应用、原核细胞糖蛋白合成等取得系列研究成果

 

人才奖项
玛莎 施华蔻女科学家奖 （2023）
开云网页登录 三八红旗手（2018）
上海市 浦江人才（2007）
東京大学農芸化学科百年纪念优秀学业奖（1995）

 

学会兼职与审稿人
中国生物化学与分子生物学会糖复合物专业委员会 副主任委员
中国生物工程学会糖生物工程专业委员会 常务委员
中国生物物理学会糖生物学分会 常务理事
中国化学会糖化学生物学专业委员会 常务委员
中国生物化学与分子生物学会蛋白质组学专业委员 委员
美国糖生物学会（SFG） 会员
亚洲糖组学研究联盟（ACGG）会员

聚焦蛋白质的O-糖基化研究，揭示蛋白质精准修饰调控机制和生物学意义，在糖基转移酶的功能发现，胞内蛋白质新型糖基化发现，疾病糖链异质体生物标志物的发现，人源糖蛋白生物合成等方面取得系列成果。张延课题组的蛋白质精准糖基化研究在国内具有独特的学科特色，揭示了与肿瘤、发育密切相关蛋白质O-糖基化修饰的精准调控机制和意义；在结直肠癌，肺癌，肝纤维化，阿尔兹海默症等疾病中研究发现基于糖链的生物标志物。
主要研究方向：
1. 肿瘤和神经发育中蛋白质的O-糖基化调控
2. 蛋白质机器中的蛋白质O-糖基化修饰过程
3. 疾病糖链生物标志物
4.人源糖蛋白的合成生物学

2025
1. Liu, Q.N., Lu, X.Y., Deng, Y., Zhang, H., Wei, R.M., Li, H.R., Feng, Y., Wei, J., Ma, F., Zhang, Y., Zou, X., Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis, Nat Commun, 2025.
2. Xu, Z., Yang, F., Xiang, B., Chang, X., Xia, D., Wu, Y., Zhang, Y., Zhang, M., Abnormal Microbial Amino Acid Metabolism and Activated Pathogenesis in Scalp with Dandruff, J Invest Dermatol, 2025.
3. Yao, B., Xu, Q., Yamada, Y., Angata, K., Zhang, Y., Narimatsu, H., Yu, D., Zhang, X., Serum O-glycosylated HBsAg levels correlate with HBV RNA in HBeAg positive CHB patients during antiviral therapy, Antiviral Res, 2025.
4. Li, X.J., Yang, F., Ma, Y.X., Zhang, M.M., Zhang, Y., Zhang, M.H., The Disturbed Microbial Niches of Itchy Scalp, J Cosmet Dermatol, 2025.

2024
5. Zhang, H., Song, K., Liu, Y., Yang, F., Lu, C., Wei, R., Xu, Z., Zou, X., Lin, L., Shi, T., Da, L.-T., Zhang, Y., Comprehensive Investigations of MUC1 O-Glycosylation Process Reveal Initial Site Preference by the Polypeptide GalNAc Transferases, Acs Catal, 2024.
6. Yin, D., Zhong, Y., Ling, S., Lu, S., Wang, X., Jiang, Z., Wang, J., Dai, Y., Tian, X., Huang, Q., Wang, X., Chen, J., Li, Z., Li, Y., Xu, Z., Jiang, H., Wu, Y., Shi, Y., Wang, Q., Xu, J., Hong, W., Xue, H., Yang, H., Zhang, Y., Da, L., Han, Z.-g., Tao, S.-c., Dong, R., Ying, T., Hong, J., Cai, Y., Dendritic-cell-targeting virus-like particles as potent mRNA vaccine carriers, Nat Biomed Eng, 2024.
7. Zhang, Z., Xu, Z., Qian, X., Chen, Y., Li, D., Qin, Z., Chen, L., Zhang, Y., Jin, Y., Ji, H., TAZ inhibits SCLC metastasis through GALNT18-mediated O-glycosylation, J Genet Genomics, 2024.
8. Xu, Z.J., Zhang, H., Tian, J.Q., Ku, X., Wei, R.M., Hou, J.L., Zhang, C., Yang, F., Zou, X., Li, Y., Kaji, H., Tao, S.C., Kuno, A., Yan, W., Da, L.T., Zhang, Y., O-glycosylation of SARS-CoV-2 spike protein by host O-glycosyltransferase strengthens its trimeric structure, Acta Bioch Bioph Sin, 2024.
9. Liu, L., Tang, Y., Zhang, Y., Wu, Q., A negatively charged region within carboxy-terminal domain maintains proper CTCF DNA binding, iScience, 2024.

2023
10. Zou, X., Lu, J., Deng, Y., Liu, Q., Yan, X., Cui, Y., Xiao, X., Fang, M., Yang, F., Sawaki, H., Sato, T., Tan, B., Lu, X., Feng, B., Kuno, A., Narimatsu, H., Gao, C., Zhang, Y., ST6GAL1 inhibits metastasis of hepatocellular carcinoma via modulating sialylation of MCAM on cell surface, Oncogene, 2023.
11. Hong, X.K., Song, K.Y., Rahman, M.U., Wei, T., Zhang, Y., Da, L.T., Chen, H.F., Phosphorylation Regulation Mechanism of β2 Integrin for the Binding of Filamin Revealed by Markov State Model, J Chem Inf Model, 2023.
12. Hong, X.K., Li, N.S., Lv, J.Y., Zhang, Y., Li, J., Zhang, J., Chen, H.F., PTMint database of experimentally verified PTM regulation on protein-protein interaction, Bioinformatics, 2023.

2022
13. Zhu, T., Gu, Q., Liu, Q., Zou, X., Zhao, H., Zhang, Y., Pu, C., Lan, M., Nanostructure stable hydrophilic hierarchical porous metal-organic frameworks for highly efficient enrichment of glycopeptides, Talanta, 2022.
14. Tan, Y., Du, H., Zhang, H., Fang, C., Jin, G., Chen, S., Wu, Q., Zhang, Y., Zhang, M., Xu, Y., Geographically Associated Fungus-Bacterium Interactions Contribute to the Formation of Geography-Dependent Flavor during High-Complexity Spontaneous Fermentation, Microbiol Spectr, 2022.
15. Li, X., Yang, F., Yan, H., Shi, Y., Chang, X., Zhang, M., Zhang, Y., Zhang, M., Microbiota profiling on itchy scalp with undetermined origin, Arch Microbiol, 2022.
16. 史婧婧, 邹霞, 张延, 淀粉样前体蛋白糖基化修饰对其加工剪切的调控, 生物技术, 2022.

2021
17. Shi, J., Ku, X., Zou, X., Hou, J., Yan, W., Zhang, Y., Comprehensive analysis of O-glycosylation of amyloid precursor protein (APP) using targeted and multi-fragmentation MS strategy, Biochim Biophys Acta Gen Subj, 2021.
18. Nagai-Okatani, C., Zou, X., Fujita, N., Sogabe, I., Arakawa, K., Nagai, M., Angata, K., Zhang, Y., Aoki-Kinoshita, K.F., Kuno, A., LM-GlycomeAtlas Ver. 2.0: An Integrated Visualization for Lectin Microarray-based Mouse Tissue Glycome Mapping Data with Lectin Histochemistry, J Proteome Res, 2021.
19. Jia, W., Zou, X., Xu, Z., Bai, L., Shan, A., Li, Y., Shi, J., Yang, F., Ding, C., Narimatsu, H., Zhang, Y., Polypeptide N-acetylgalactosaminyltransferase 18 Retains in Endoplasmic Reticulum Depending on its Luminal Regions Interacting with ER resident UGGT1, PLOD3 and LPCAT1, Glycobiology, 2021.
20. 张涵, 张延, 糖蛋白药物的生产与糖链改造, 开云网页登录 学报, 2021.
21. 杨芳, 李雪静, 马英鑫, 张萌萌, 张梦晖, 张延, 人头皮微生物与相关头皮疾病的研究进展, 生命的化学, 2021.
22. 邓陶, 刘倩楠, 邹霞, 张延, 基于末端糖链的疾病诊疗新技术, 开云网页登录 学报, 2021.

2020
23. Xu, Z., Ku, X., Tomioka, A., Xie, W., Liang, T., Zou, X., Cui, Y., Sato, T., Kaji, H., Narimatsu, H., Yan, W., Zhang, Y., O-linked N-acetylgalactosamine modification is present on the tumor suppressor p53, Biochim Biophys Acta Gen Subj, 2020.
24. Liang, T., Xu, Z., Jia, W., Zhang, H., Yang, F., Zou, X., Zhang, Y., A simple bacterial expression system for human ppGalNAc-T and used for the synthesis of O-GalNAc glycosylated interleukin 2, Biochem Biophys Res Commun, 2020.
25. Li, X., Xu, Z., Hong, X., Zhang, Y., Zou, X., Databases and Bioinformatic Tools for Glycobiology and Glycoproteomics, Int J Mol Sci, 2020.

2019
26. Zou, X., Yao, F., Yang, F., Zhang, F., Xu, Z., Shi, J., Kuno, A., Zhao, H., Zhang, Y., Glycomic Signatures of Plasma IgG Improve Preoperative Prediction of the Invasiveness of Small Lung Nodules, Molecules, 2019.
27. Zhou, L., Zhang, S., Zou, X., Lu, J., Yang, X., Xu, Z., Shan, A., Jia, W., Liu, F., Yan, X., Su, H., Liang, T., Zheng, M., Zhang, Y., Feng, B., The beta-galactoside alpha2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation, Cancer Manag Res, 2019.
28. Zhang, S., Bai, L., Chen, Q., Ren, Y., Zhang, K., Wu, Q., Huang, H., Li, W., Zhang, Y., Zhang, J., Liu, Y., Identification of the O-GalNAcylation site(s) on FOXA1 catalyzed by ppGalNAc-T2 enzyme in vitro, Biochem Biophys Res Commun, 2019.
29. Tian, J.Q., Liu, F., Xu, Z.J., Shi, J.J., Liang, T., Zhang, Y., Da, L.T., Regulatory Role of One Critical Catalytic Loop of Polypeptide N-Acetyl-Galactosaminyltransferase-2 in Substrate Binding and Catalysis during Mucin-Type O-Glycosylation, Acs Catal, 2019.
30. Shan, A.D., Lu, J.S., Xu, Z.J., Li, X., Xu, Y.J., Li, W., Liu, F., Yang, F., Sato, T., Narimatsu, H., Zhang, Y., Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation, Bba-Gen Subjects, 2019.
31. Liu, F., Cui, Y., Yang, F., Xu, Z., Da, L.T., Zhang, Y., Inhibition of polypeptide N-acetyl-alpha-galactosaminyltransferases is an underlying mechanism of dietary polyphenols preventing colorectal tumorigenesis, Bioorg Med Chem, 2019.

2018
32. Zhu, M.Y., Chen, P.Z., Li, J., Yu, D.M., Huang, D., Zhu, X.J., Han, Y., Chen, J., Huang, W., Chen, Y.Y., Gong, Q.M., Jiang, J.H., Zhang, D.H., Zhang, Y., Zhang, J.M., Zhang, X.X., Serum M2BPGi level is a novel predictive biomarker for the responses to pegylated interferon-alpha treatment in HBeAg-positive chronic hepatitis B patients, J Med Virol, 2018.
33. Yan, X.L., Lu, J.S., Zou, X., Zhang, S., Cui, Y.L., Zhou, L.Q., Liu, F., Shan, A.D., Lu, J.Y., Zheng, M.H., Feng, B., Zhang, Y., The polypeptide N-acetylgalactosaminyltransferase 4 exhibits stage-dependent expression in colorectal cancer and affects tumorigenesis, invasion and differentiation, Febs J, 2018.
34. Xu, W.P., Wang, Z.R., Zou, X., Zhao, C., Wang, R., Shi, P.M., Yuan, Z.L., Yang, F., Zeng, X., Wang, P.Q., Sultan, S., Zhang, Y., Xie, W.F., Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein evaluates liver function and predicts prognosis in liver cirrhosis, J Dig Dis, 2018.
35. Wang, X.S., Du, H., Zhang, Y., Xu, Y., Environmental Microbiota Drives Microbial Succession and Metabolic Profiles during Chinese Liquor Fermentation, Appl Environ Microb, 2018.
36.崔雅璐，徐颖娇，贾文娟，杨芳, 张延 疾病及发育中多肽:N-乙酰氨基半乳糖转移酶ppGalNAc-T的重要性, 生命科学, 2018.

2017
37. Zou, X., Zhu, M.Y., Yu, D.M., Li, W., Zhang, D.H., Lu, F.J., Gong, Q.M., Liu, F., Jiang, J.H., Zheng, M.H., Kuno, A., Narimatsu, H., Zhang, Y., Zhang, X.X., Serum WFA+ -M2BP levels for evaluation of early stages of liver fibrosis in patients with chronic hepatitis B virus infection, Liver Int, 2017.
38. Zou, X., Yoshida, M., Nagai-Okatani, C., Iwaki, J., Matsuda, A., Tan, B., Hagiwara, K., Sato, T., Itakura, Y., Noro, E., Kaji, H., Toyoda, M., Zhang, Y., Narimatsu, H., Kuno, A., A standardized method for lectin microarray-based tissue glycome mapping, Sci Rep, 2017.
39. Zhu, M.Y., Zou, X., Li, Q., Yu, D.M., Yang, Z.T., Huang, D., Chen, J., Gong, Q.M., Zhang, D.H., Zhang, Y., Chen, L., Chen, P.Z., Zhang, X.X., A novel noninvasive algorithm for the assessment of liver fibrosis in patients with chronic hepatitis B virus infection, J Viral Hepat, 2017.
40. Zhang, S., Lu, J., Xu, Z., Zou, X., Sun, X., Xu, Y., Shan, A., Lu, J., Yan, X., Cui, Y., Yan, W., Du, Y., Gu, J., Zheng, M., Feng, B., Zhang, Y., Differential expression of ST6GAL1 in the tumor progression of colorectal cancer, Biochem Biophys Res Commun, 2017.
41. Xu, Z.J., Li, X., Zhou, S.M., Xie, W.X., Wang, J., Cheng, L., Wang, S., Guo, S.J., Xu, Z.W., Cao, X., Zhang, M.H., Yu, B.A., Narimatsu, H., Tao, S.C., Zhang, Y., Systematic identification of the protein substrates of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T1/T2/T3 using a human proteome microarray, Proteomics, 2017.
42. Song, Z., Du, H., Zhang, Y., Xu, Y., Unraveling Core Functional Microbiota in Traditional Solid-State Fermentation by High-Throughput Amplicons and Metatranscriptomics Sequencing, Front Microbiol, 2017.
43. Liu, F., Xu, K., Xu, Z.J., de las Rivas, M., Wang, C.R., Li, X., Lu, J.S., Zhou, Y.Y., Delso, I., Merino, P., Hurtado-Guerrero, R., Zhang, Y., Wu, F., The small molecule luteolin inhibits N-acetyl--galactosaminyltransferases and reduces mucin-type O-glycosylation of amyloid precursor protein, J Biol Chem, 2017.
44. 张芳, 许之珏, 徐颖姣, 邹霞, 张延, IgG糖基化与疾病相关性研究进展, 生命科学, 2017.

2016
45. Xu, Z.J., Wang, Z.X., Yuan, C., Liu, X.P., Yang, F., Wang, T., Wang, J.L., Manabe, K., Qin, O., Wang, X.M., Zhang, Y., Zhang, M.H., Dandruff is associated with the conjoined interactions between host and microorganisms, Sci Rep-Uk, 2016.
46. Xu, Y., Pang, W., Lu, J., Shan, A., Zhang, Y., Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin, J Biol Chem, 2016.
47. Wang, Y., Cao, Y.F., Huang, X.Y., Yu, T., Wei, Z.Y., McGrath, J., Xu, F., Bi, Y., Li, X.W., Yang, F.P., Li, W.D., Zou, X., Peng, Z.H., Xiao, Y.Z., Zhang, Y., He, L., He, G., Allele-specific expression of mutated in colorectal cancer (MCC) gene and alternative susceptibility to colorectal cancer in schizophrenia, Sci Rep-Uk, 2016.
48. 鲁飞杰, 许之珏, 邹霞, 郭勋祥, 张延, 一种新型末端炔基修饰磁珠的合成及其在糖肽富集中的应用, 开云网页登录 学报(医学版), 2016.

2015
49. Lu, X.W., Wu, Q., Zhang, Y., Xu, Y., Genomic and transcriptomic analyses of the Chinese Maotai-flavored liquor yeast MT1 revealed its unique multi-carbon co-utilization, Bmc Genomics, 2015.
50. 张东华, 朱雪娟, 邹霞, 张延, 张欣欣, 于德敏, α1-酸性糖蛋白糖链检测对慢乙肝相关肝硬化的早期诊断及其临床应用, 现代免疫学, 2015.

2014
51. Zou, X., Chi, X., Pan, Y., Du, D., Sun, H., Matsuda, A., Li, W., Kuno, A., Zhang, X., Narimatsu, H., Niu, J., Zhang, Y., LecT-Hepa facilitates estimating treatment outcome during interferon therapy in chronic hepatitis C patients, Clinical proteomics, 2014.
52. Yu, D.M., Li, X.H., Mom, V., Lu, Z.H., Liao, X.W., Han, Y., Pichoud, C., Gong, Q.M., Zhang, D.H., Zhang, Y., Deny, P., Zoulim, F., Zhang, X.X., N-glycosylation mutations within hepatitis B virus surface major hydrophilic region contribute mostly to immune escape, J Hepatol, 2014.
53. Tan, B., Matsuda, A., Zhang, Y., Kuno, A., Narimatsu, H., Multilectin-assisted fractionation for improved single-dot tissue glycome profiling in clinical glycoproteomics, Mol Biosyst, 2014.
54. Kong, Y., Wu, Q., Zhang, Y., Xu, Y., In Situ Analysis of Metabolic Characteristics Reveals the Key Yeast in the Spontaneous and Solid-State Fermentation Process of Chinese Light-Style Liquor, Appl Environ Microb, 2014.
55. 申浩, 张秀, 张蕾, 张延, 代谢性标记结合二维电泳寻找O-糖基化蛋白的研究, 生命开云足球app官方下载安装 , 2014.

2013
56. Zou, X., Feng, B., Dong, T.T., Yan, G.Q., Tan, B.B., Shen, H., Huang, A., Zhang, X., Zhang, M.H., Yang, P.Y., Zheng, M.H., Zhang, Y., Up-regulation of type I collagen during tumorigenesis of colorectal cancer revealed by quantitative proteomic analysis, Journal of Proteomics, 2013.
57. Zhu, X.J., Gong, Q.M., Yu, D.M., Zhang, D.H., Gu, L.L., Han, Y., Chen, J., Zhang, Y., Zhang, X.X., Early serum hepatitis B virus large surface protein level: A stronger predictor of virological response to peginterferon alfa-2a than that to entecavir in HBeAg-positive patients with chronic hepatitis B, Journal of Clinical Virology, 2013.
58. Zhang, X., Zhang, Y., Applications of Azide-Based Bioorthogonal Click Chemistry in Glycobiology, Molecules, 2013.
59. Tan, B.B., Qiu, Y.P., Zou, X., Chen, T.L., Xie, G.X., Cheng, Y., Dong, T.T., Zhao, L.J., Feng, B., Hu, X.F., Xu, L.X., Zhao, A.H., Zhang, M.H., Cai, G.X., Cai, S.J., Zhou, Z.X., Zheng, M.H., Zhang, Y., Jia, W., Metabonomics Identifies Serum Metabolite Markers of Colorectal Cancer, Journal of Proteome Research, 2013.
60. Aoki-Kinoshita, K.F., Sawaki, H., An, H.J., Campbell, M., Cao, Q.C., Cummings, R., Hsu, D.K., Kato, M., Kawasaki, T., Khoo, K.H., Kim, J., Kolarich, D., Li, X.Y., Liu, M.Q., Matsubara, M., Okuda, S., Packer, N.H., Ranzinger, R., Shen, H.L., Shikanai, T., Shinmachi, D., Toukach, P., Yamada, I., Yamaguchi, Y., Yang, P.Y., Ying, W.T., Yoo, J.S., Zhang, Y., Zhang, Y., Narimatsu, H., The Fifth ACGG-DB Meeting Report: Towards an International Glycan Structure Repository, Glycobiology, 2013.

2012
61. Wang, S., Xie, W.X., Zhang, X., Zou, X., Zhang, Y., Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides, Chem Commun, 2012.
62. Li, X., Wang, J., Li, W., Xu, Y.J., Shao, D., Xie, Y.Y., Xie, W.X., Kubota, T., Narimatsu, H., Zhang, Y., Characterization of ppGalNAc-T18, a member of the vertebrate-specific Y subfamily of UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases, Glycobiology, 2012.
63. Du, D.N., Zhu, X.J., Kuno, A., Matsuda, A., Tsuruno, C., Yu, D.M., Zhang, Y., Ikehara, Y., Tanaka, Y., Zhang, X.X., Narimatsu, H., Comparison of LecT-Hepa and FibroScan for assessment of liver fibrosis in hepatitis B virus infected patients with different ALT levels, Clin Chim Acta, 2012.
64. Cheng, Y., Xie, G.X., Chen, T.L., Qiu, Y.P., Zou, X., Zheng, M.H., Tan, B.B., Feng, B., Dong, T.T., He, P.A., Zhao, L.J., Zhao, A.H., Xu, L.X., Zhang, Y., Jia, W., Distinct Urinary Metabolic Profile of Human Colorectal Cancer, Journal of Proteome Research, 2012.

2011-2010
65. 王静, 彭灿, 张延, O-糖基化起始糖基转移酶的活性与结构研究, 生命科学, 2011.
66. Zhang, X.W., Yan, X.J., Zhou, Z.R., Yang, F.F., Wu, Z.Y., Sun, H.B., Liang, W.X., Song, A.X., Lallemand-Breitenbach, V., Jeanne, M., Zhang, Q.Y., Yang, H.Y., Huang, Q.H., Zhou, G.B., Tong, J.H., Zhang, Y., Wu, J.H., Hu, H.Y., de The, H., Chen, S.J., Chen, Z., Arsenic Trioxide Controls the Fate of the PML-RAR alpha Oncoprotein by Directly Binding PML, Science, 2010.
67. Wang, S., Zou, X., Zhang, Y., Mass Spectrometry Based Analysis of Protein O-glycosylation, Prog Chem, 2010.
68. Peng, C., Togayachi, A., Kwon, Y.D., Xie, C.Y., Wu, G.D., Zou, X., Sato, T., Ito, H., Tachibana, K., Kubota, T., Noce, T., Narimatsu, H., Zhang, Y., Identification of a novel human UDP-GalNAc transferase with unique catalytic activity and expression profile, Biochem Bioph Res Commun, 2010.

2009-2006
69. Zhang, Q.Y., Mao, J.H., Liu, P., Huang, Q.H., Lu, J., Xie, Y.Y., Weng, L., Zhang, Y., Chen, Q., Chen, S.J., Chen, Z., A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia, P Natl Acad Sci USA, 2009.
70. Wei, H., Shen, J., Pang, X., Ding, D., Zhang, Y., Zhang, B., Lu, H., Wang, T., Zhang, C., Hua, X., Cui, L., Zhao, L., Fatal infection in human flora-associated piglets caused by the opportunistic pathogen Klebsiella pneumoniae from an apparently healthy human donor, J Vet Med Sci, 2008.
71. Li, M., Wang, B.H., Zhang, M.H., Rantalainen, M., Wang, S.Y., Zhou, H.K., Zhang, Y., Shen, J., Pang, X.Y., Zhang, M.L., Wei, H., Chen, Y., Lu, H.F., Zuo, J., Su, M.M., Qiu, Y.P., Jia, W., Xiao, C.N., Smith, L.M., Yang, S.L., Holmes, E., Tang, H.R., Zhao, G.P., Nicholson, J.K., Li, L.J., Zhao, L.P., Symbiotic gut microbes modulate human metabolic phenotypes, P Natl Acad Sci USA, 2008.
72. 邵栋, 谢春燕, 程腊梅, 成松久, 张延, 一种与多肽：N-乙酰氨基半乳糖转移酶结构类似基因的研究, 2008年全国糖生物学学术会议, 中国江苏苏州, 2008, p. 1.
73. Zhang, M.L., Liu, B.Y., Zhang, Y., Wei, H., Lei, Y.F., Zhao, L.P., Structural shifts of mucosa-associated lactobacilli and Clostridium leptum subgroup in patients with ulcerative colitis, J Clin Microbiol, 2007.
74. Li, K., Guan, W., Wei, G., Liu, B., Xu, J., Zhao, L., Zhang, Y., Phylogenetic analysis of intestinal bacteria in the Chinese mitten crab (Eriocheir sinensis), J Appl Microbiol, 2007.
75. Shen, J., Zhang, B.R., Wei, G.F., Pang, X., Wei, H., Li, M., Zhang, Y., Jia, W., Zhao, L.P., Molecular profiling of the Clostridium leptum subgroup in human fecal microflora by PCR-denaturing gradient gel electrophoresis and clone library analysis, Appl Environ Microb, 2006.

Before 2006
76. Cheng, L.M., Tachibana, K., Iwasaki, H., Kameyama, A., Zhang, Y., Kubota, T., Hiruma, T., Tachibana, K., Kudo, T., Guo, J.M., Narimatsu, H., Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15, Febs Lett, 2004.
77. Zhang, Y., Iwasaki, H., Wang, H., Kudo, T., Kalka, T.B., Hennet, T., Kubota, T., Cheng, L.M., Inaba, N., Gotoh, M., Togayachi, A., Guo, J.M., Hisatomi, H., Nakajima, K., Nishihara, S., Nakamura, M., Marth, J.D., Narimatsu, H., Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine : polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen, J Biol Chem, 2003.
78. Wang, H., Tachibana, K., Zhang, Y., Iwasaki, H., Kameyama, A., Cheng, L.M., Guo, J.M., Hiruma, T., Togayachi, A., Kudo, T., Kikuchi, N., Narimatsu, H., Cloning and characterization of a novel UDP-GaINAc : polypeptide N-acetylgalactosaminyltransferase, pp-GaINAc-T14, Biochem Bioph Res Co, 2003.
79. Iwasaki, H., Zhang, Y., Tachibana, K., Gotoh, M., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Kubota, T., Narimatsu, H., Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine: Polypeptide N-acetylgalactosaminyltransferase 2, J Biol Chem, 2003.
80. Guo, P., Zhang, Y., Zhang, X.Y., Chen, H.L., Zhang, Y., Wang, H., Narimatsu, H., Analysis of lewis antigens on cell surface and alpha1,3 fucosyltransferase subtypes in H7721 human hepatocarcinoma cells, J Exp Clin Cancer Res, 2003.
81. Kudo, T., Iwai, T., Kubota, T., Iwasaki, H., Takayma, Y., Hiruma, T., Inaba, N., Zhang, Y., Gotoh, M., Togayachi, A., Narimatsu, H., Molecular cloning and characterization of a novel UDP-Gal : GaINAc alpha peptide beta 1,3-galactosyltransferase (ClGal-T2), an enzyme synthesizing a core 1 structure of O-glycan, J Biol Chem, 2002.
82. Iwai, T., Inaba, N., Naundorf, A., Zhang, Y., Gotoh, M., Iwasaki, H., Kudo, T., Togayachi, A., Ishizuka, Y., Nakanishi, H., Narimatsu, H., Molecular cloning and characterization of a novel UDP-GlcNAc: GalNAc-peptide,beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans, J Biol Chem, 2002.
83. Hagiwara, H., Kunihiro, S., Nakajima, K., Sano, M., Masaki, H., Yamamoto, M., Pak, J.W., Zhang, Y., Takase, K., Kuwabara, I., Maruyama, I.N., Machida, M., Affinity selection of DNA-binding proteins from yeast genomic DNA libraries by improved lambda phage display vector, J Biochem, 2002.
84. Guo, J.M., Zhang, Y., Cheng, L.M., Iwasaki, H., Wang, H., Kubota, T., Tachibana, K., Narimatsu, H., Molecular cloning and characterization of a novel member of the UDP-GalNAc : polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12, Febs Lett, 2002.
85. Cheng, L.M., Tachibana, K., Zhang, Y., Guo, J., Tachibana, K.K., Kameyama, A., Wang, H., Hiruma, T., Iwasaki, H., Togayachi, A., Kudo, T., Narimatsu, H., Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10, Febs Lett, 2002.
86. Zhang, Y., Pak, J.W., Maruyama, I.N., Machida, M., Affinity selection of DNA-binding proteins displayed on bacteriophage lambda, J Biochem, 2000.
87. Nakajima, K., Kunihiro, S., Sano, M., Zhang, Y., Eto, S., Chang, Y.C., Suzuki, T., Jigami, Y., Machida, M., Comprehensive cloning and expression analysis of glycolytic genes from the filamentous fungus, Aspergillus oryzae, Curr Genet, 2000.
88. Zhang, Y., Arai, H., Sambongi, Y., Igarashi, Y., Kodama, T., Heterologous expression of Hydrogenobacter thermophilus cytochrome c-552 in the periplasm of Pseudomonas aeruginosa, J Ferment Bioeng, 1998.
89. Toshiaki Kimura , Yan Zhang , Tohru Kodama , Toshio Omori Isolation and characterization of Tn 5-induced mutants deficient in carbazole catabolism., FEMS Microbiology Letters, 1996.
90. Arai H. ,Zhang, Y. , Sambongi Y. , Igarashi Y. , Kodama T., Production of Recombinant Cytochrome c-551 in a Pseudomonas aeruginosa Mutant Strain., Journal of Fermentation & Bioengineering, 1995.
91. Ouchiyama, N., Zhang, Y., Omori, T., Kodama, T., Biodegradation of Carbazole by Pseudomonas spp. CA06 and CA10, Bioscience, Biotechnology, and Biochemistry, 1993.
92. 孙韦强, 张延, 余正齐, 汪莉, 杨钧, 尹光琳, 李族光, 利用微生物转化丙烯腈成丙烯酰胺的研究Ⅱ、产腈水合酶菌种的发酵条件的研究, 石油学报(石油加工), 1989.
93. 孙韦强, 伍登熙, 尹光琳, 余正齐, 李族光, 张刚, 张延, 周建龙, 孙俊, 陆光, 汪莉, 杨芳晓, 杨钧, 利用微生物转化丙烯腈成丙烯酰胺的研究Ⅰ.产腈水合酶菌种的分离筛选和鉴定, 石油学报(石油加工), 1988.
94. 张延, 刘学东，包俊, 利用细菌淀粉酶常压蒸煮生产酒精, 山东大学学生学报 求索, 1985.

学术书籍：
1.《糖组学手册》中文导读 科学书版社 2011年6月第一版
2.《2012-2013生物化学与分子生物学学科发展报告》 参编 中国科学技术出版社 2014年4月第一版
3. 参编书籍，2022年1月出版 Tissue Glycome Mapping: Lectin Microarray-Based Differential Glycomic Analysis of Formalin-Fixed Paraffin-Embedded Tissue Sections. Glycan Microarrays. Methods in Molecular Biology, vol 2460. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2148-6_10

国家自然科学基金面上项目，ppGalNAc-T18调控细胞O-糖基化蛋白质成熟分泌过程的作用机制研究，2021，项目负责人
国家自然科学基金面上项目，神经特异性O-GalNAc糖基转移酶在内质网中的功能机制研究，2018，项目负责人
国家自然科学基金面上项目，蛋白质O-GalNAc糖基化抑制剂的分子机制研究，2016，项目负责人
国家自然科学基金面上项目，内质网中ppGalNAc-T18的功能机制研究，2014，项目负责人
国家自然科学基金面上项目，胞浆或核定位蛋白质的O-GalNAc糖基化研究，2012，项目负责人
国家自然科学基金面上项目，P19细胞神经分化相关ppGalNAc-T13的功能解析，2010，项目负责人
国家自然科学基金面上项目，ppGalNAc-T在肺癌中的功能研究，2008，项目负责人
十三五国家科技重大专项“艾滋病和病毒性肝炎等重大传染病防治”专项，乙肝相关肝癌异常糖链糖蛋白的新型凝集素识别技术开发与临床精准检测应用，2018，子课题负责人
国家国际科技合作政府间项目，基于糖链生物标志物的疾病早期诊断新技术，2012，项目负责人
国家重点基础研究发展计划973前沿，糖链对肿瘤细胞生物学行为的影响及机制研究，2012，子课题负责人
国家高技术研究发展计划863计划，凝集素芯片开发与糖链结构验证，2012，子课题负责人
国家重点基础研究发展计划973蛋白质重大项目，疾病以及药物治疗下蛋白质表达谱及其与代谢表达谱的相关性研究，2007，课题负责人
上海市科委浦江人才计划，多肽N乙酰氨基半乳糖基转移酶在肿瘤发生发展中的功能研究，2007，项目负责人

张延，梁涛，许之珏，贾文娟。一种制备N-乙酰氨基半乳糖转移酶的方法，专利申请号：CN2019112670153，PCT国际申请号：PCT/CN2020/128291
张延, 张芳, 许之珏, 杨芳, 邹霞, 姚烽, 赵珩。血清免疫球蛋白G糖链修饰在肺部磨玻璃结节早期诊断中的用途。专利申请号：CN201711070938.0
邹霞，张延，杨芳，冯波，郑民华。CTx在制备诊断结直肠癌药物中的用途。中国发明专利，专利号：ZL201310476530.9
张延，王胜，谢文娴。富集叠氮标记生物大分子的磁性纳米材料及其制备与应用。中国发明专利，专利号：ZL201110236722.3
张延，庞文杰。一种针对ppGalNAc-T13多克隆抗体的特异性抗原肽及其制备与应用。中国发明专利，专利号：ZL201110236821.1
张延，彭灿，武功冬，邹霞，谢文娴。ppGalNAc-T20抗原及其多克隆抗体的制备方法。中国发明专利，专利号：ZL201010300097.X
成松久、张延。N-乙酰氨基半乳糖胺转移酶的突变体。日本发明专利，专利号：4251402

获博士学位8人，获硕士学位13人，博士后出站3人

2009年，武功冬，开云网页登录 杨臣勋校友奖学金
2010年，王 胜，上海市博士后基金面上项目
2011年，王 胜，国家第49批博士后基金
2012年，谭斌斌，教育部国家留学基金
2013年，谭斌斌，博士研究生国家奖学金
2013年，邹 霞，开云网页登录 研究生优秀奖学金（博士生）
2013年，谭斌斌，开云网页登录 三好学生
2013年，李 星，金龙鱼企业奖学金（博士生）
2014年，邹 霞，国家第56批博士后基金
2014年，谭斌斌，开云网页登录 优秀毕业生
2015年，刘 峰，开云网页登录 优博新生奖
2016年，徐颖娇，开云网页登录 优秀毕业生
2016年，许之珏，博士研究生国家奖学金
2017年，许之珏，上海市优秀毕业生
2017年，陆吉顺，第61批博士后基金
2017年，陆吉顺，国家自然科学基金青年基金
2018年，邹霞，上海市杨帆计划
2018年，许之珏，上海市超级博士后
2018年，许之珏，第64批博士后基金
2018年，刘 峰，博士研究生国家奖学金
2018年，邹 霞，上海市青年科技英才扬帆计划
2018年，梁 涛，学业优秀一等奖学金
2018年，梁 涛，SMC高田奖学金
2018年，梁 涛，开云网页登录 校优秀团干部
2019年，刘 峰，开云网页登录 优秀毕业生 （博士生）
2020年，史婧婧，学业优秀一等奖学金
2024年，张涵， 开云网页登录 优秀毕业生 （博士生）

学生学术会议优秀海报奖/最佳学术论文奖：
李星，2012年第六届亚太人类蛋白质组大会，2012.5.5-2012.5.7，中国北京
徐颖姣，2012年全国糖生物学学术会议，2012.8.4-2012.8.7，浙江温州
许之珏，2015年第七届亚洲糖生物学组织联盟ACGG年会，2015.11.12~15，日本仙台
刘峰，2016年第八届亚洲糖生物学组织联盟ACGG年会，2016.10.13-16，中国无锡
刘峰，2016年全国糖生物学学术会议，2016.08.05-07，中国南通
许之珏、刘峰，2017年第九届亚洲糖生物学组织联盟ACGG年会，2017.12.17-20，中国香港
刘峰，2018年全国糖生物学学术会议，2018.09.21-23，中国上海
许之珏，2018年第十一届国际糖基转移酶研讨会，2018.06.19-23，中国青岛
史婧婧，2019年第十一届亚洲糖生物学组织联盟ACGG年会，2019.11.11-14，韩国釜山
贾文娟，2020年全国糖生物学学术会议，2020.09.19-21，中国无锡

毕业博士生获国家自然科学基金情况：
2017年，谭斌斌，国家自然科学基金青年基金
2018年，徐颖娇，国家自然科学基金青年基金
2018年，邹 霞，国家自然科学基金青年基金
2020年，刘 峰，国家自然科学基金青年基金
2020年，许之珏，国家自然科学基金青年基金